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Herbert Schöchl Selected Research

Prothrombin (Factor II)

10/2021Reversing Rivaroxaban Anticoagulation as Part of a Multimodal Hemostatic Intervention in a Polytrauma Animal Model.
11/2020Sufficient Thrombin Generation Despite 95% Hemodilution: An In Vitro Experimental Study.
10/2020Effectiveness of prothrombin complex concentrate for the treatment of bleeding: A systematic review and meta-analysis.
1/2019Evaluation of combined idarucizumab and prothrombin complex concentrate treatment for bleeding related to dabigatran in a lethal porcine model of double trauma.
1/2019Prothrombin Complex Concentrate-induced Disseminated Intravascular Coagulation Can Be Prevented by Coadministering Antithrombin in a Porcine Trauma Model.
3/2017Dual inhibition of thrombin and activated factor X attenuates disseminated intravascular coagulation and protects organ function in a baboon model of severe Gram-negative sepsis.
10/2015Effect of coagulation factor concentrate administration on ROTEM® parameters in major trauma.
7/2014Endogenous thrombin potential following hemostatic therapy with 4-factor prothrombin complex concentrate: a 7-day observational study of trauma patients.
5/2014Tranexamic acid, fibrinogen concentrate, and prothrombin complex concentrate: data to support prehospital use?
10/2013Impact of fibrinogen concentrate alone or with prothrombin complex concentrate (+/- fresh frozen plasma) on plasma fibrinogen level and fibrin-based clot strength (FIBTEM) in major trauma: a retrospective study.
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Herbert Schöchl Research Topics

Disease

45Wounds and Injuries (Trauma)
05/2022 - 01/2010
30Hemorrhage
04/2022 - 07/2010
8Shock
01/2020 - 02/2002
7Tics (Tic)
04/2022 - 09/2010
6Thrombosis (Thrombus)
01/2022 - 09/2012
6Hemorrhagic Shock
11/2020 - 07/2010
5Traumatic Brain Injuries (Traumatic Brain Injury)
09/2021 - 05/2014
4Acidosis
10/2015 - 07/2011
3Disseminated Intravascular Coagulation
01/2019 - 11/2015
3Hypothermia
05/2014 - 07/2011
2Inflammation (Inflammations)
01/2022 - 03/2017
2Traumatic Shock
01/2022 - 06/2011
2Multiple Trauma (Multiple Injuries)
10/2021 - 05/2017
2Sepsis (Septicemia)
01/2019 - 03/2017
2Hypotension (Low Blood Pressure)
10/2015 - 08/2013
2Hypovolemia
07/2010 - 02/2002
1Critical Illness (Critically Ill)
12/2021
1Gastric Dilatation (Stomach Dilatation)
07/2020
1Thrombophilia
01/2020
1Genetic Predisposition to Disease (Genetic Predisposition)
01/2020
1Cerebral Hemorrhage
02/2019
1Thromboembolism
02/2019
1Septic Shock (Toxic Shock Syndrome)
01/2019
1Postoperative Hemorrhage
01/2019
1Contusions
01/2019
1Hip Fractures (Intertrochanteric Fractures)
01/2019
1Atrial Fibrillation
09/2016
1Stroke (Strokes)
09/2016
1Acute-Phase Reaction
03/2016
1Acute Promyelocytic Leukemia
11/2015
1Asphyxia (Suffocation)
11/2015
1Ischemia
11/2015
1Drowning
11/2015
1Hypoxia (Hypoxemia)
11/2015

Drug/Important Bio-Agent (IBA)

23Fibrinogen (Factor I)FDA Link
04/2022 - 01/2010
14Hemostatics (Antihemorrhagics)IBA
10/2021 - 07/2010
14Prothrombin (Factor II)IBA
10/2021 - 01/2010
13Blood Coagulation Factors (Coagulation Factor)IBA
04/2022 - 01/2010
10AnticoagulantsIBA
01/2022 - 09/2016
8Tranexamic Acid (AMCA)FDA Link
04/2022 - 04/2013
5FibrinIBA
10/2015 - 04/2012
4ThrombinFDA Link
11/2020 - 07/2014
3idarucizumabIBA
08/2021 - 01/2019
3Vitamin KFDA Link
01/2019 - 05/2014
2Factor XIII (Coagulation Factor XIII)IBA
01/2022 - 07/2013
2Heparitin Sulfate (Heparan Sulfate)IBA
01/2022 - 11/2019
2Tissue Plasminogen Activator (Alteplase)FDA Link
01/2020 - 11/2015
2Epinephrine (Adrenaline)FDA LinkGeneric
11/2019 - 01/2018
2Syndecan-1 (Syndecan 1)IBA
11/2019 - 01/2018
2AntithrombinsIBA
01/2019 - 03/2017
2prothrombin complex concentrates (PPSB)IBA
01/2019 - 07/2011
2fibrin fragment D (D-dimer)IBA
03/2017 - 11/2015
2Crystalloid SolutionsIBA
10/2015 - 08/2012
2antineoplaston A10 (A 10)IBA
10/2015 - 01/2011
2Starch (Cornstarch)IBA
02/2011 - 02/2002
1Platelet Aggregation Inhibitors (Antiplatelet Drugs)IBA
05/2022
1Proteins (Proteins, Gene)FDA Link
01/2022
1Heparin (Liquaemin)FDA LinkGeneric
01/2022
1Heparin Lyase (heparin lyase)IBA
01/2022
1Factor Xa InhibitorsIBA
10/2021
1RivaroxabanIBA
10/2021
1Adenosine Diphosphate (ADP)IBA
09/2021
1PRT064445IBA
08/2021
1InterleukinsIBA
05/2021
1Protein CIBA
01/2020
1Thromboplastin (Tissue Factor)IBA
01/2020
1Vascular Endothelial Growth Factor Receptor-1 (fms-Like Tyrosine Kinase)IBA
11/2019
1Plasminogen Activators (Plasminogen Activator)IBA
01/2019
1Warfarin (Coumadin)FDA LinkGeneric
01/2019
1DabigatranFDA Link
01/2019
1Antifibrinolytic Agents (Antifibrinolytics)IBA
05/2017
1PlasminogenIBA
05/2017
1Factor Xa (Coagulation Factor Xa)IBA
03/2017
1Factor X (Stuart Factor)IBA
03/2017
1Dacarbazine (DIC)FDA LinkGeneric
03/2017
1CatecholaminesIBA
03/2017
1Pharmaceutical PreparationsIBA
09/2016
1Colloids (Colloid)IBA
10/2015
1Dihydrotachysterol (AT 10)IBA
10/2015
1Hemoglobins (Hemoglobin)IBA
07/2013
1Cytochalasin DIBA
07/2013
1Deamino Arginine Vasopressin (Desmopressin)FDA LinkGeneric
07/2011
1Anesthetics (Anesthetic Agents)IBA
06/2011
1IsofluraneFDA LinkGeneric
06/2011

Therapy/Procedure

23Therapeutics
04/2022 - 07/2010
11Resuscitation
09/2021 - 02/2002
4Hemodilution
04/2015 - 09/2010
3Critical Care (Surgical Intensive Care)
12/2021 - 04/2012
2Airway Management
07/2020 - 08/2019
2Operative Surgical Procedures
01/2019 - 05/2017
2Laparotomy
06/2011 - 10/2010
1Erythrocyte Transfusion
10/2020
1Length of Stay
01/2019
1Blood Transfusion (Blood Transfusions)
05/2017
1Cardiopulmonary Resuscitation (CPR)
11/2015
1Injections
06/2015
1Perioperative Care
04/2015
1Aftercare (After-Treatment)
04/2015
1Cardiopulmonary Bypass (Heart-Lung Bypass)
04/2012
1Coronary Artery Bypass (Coronary Artery Bypass Surgery)
04/2012